David C. Truong
David C. Truong, M.S.

Programmer/Analyst V
Computational Sciences Manager

M.S., Computer and Electrical Engineering, California State University Long Beach, 1985.
M.S., Applied Mathematics, University of Sai Gon, Faculty of Sciences, Viet Nam, 1975.
B.S., Computer Science, California State University Long Beach, 1983.

"JANUS: A Java/Internet-based Nuclear Medicine Computing System," 3rd Place, Scientific Exhibit, Society of Nuclear Medicine Annual Meeting, Toronto, 1998.
Staff Incentive Award for outstanding performance and contributions, UCLA Department of Molecular & Medical Pharmacology, 1995-1996, 1998-1999.
Software System Engineer of the year for 1991 candidate, Rockwell International, Software System Department, 1991.
Sustained Superior Performance, Rockwell International, Software System Department, 1990.


Address

Department of Molecular & Medical Pharmacology
UCLA School of Medicine
10833 LeConte Ave., MS B2-086 CHS
Los Angeles, CA 90095-6948

Phone: (310) 825-2133
Fax:   (310) 825-4517

Email: dtruong@mednet.ucla.edu
Website: http://dragon.nuc.ucla.edu

Areas of Interest

  • Java/Internet based system
  • Image Archival/Retrieval/Analysis system
  • Image reconstruction
  • Kinetic Imaging system
  • Client/Server database & computing
  • System/Network communications & management
  • Graphical User Interface development
  • Data Portal

    The Web Image Retrieval, Image Clinical/Research Database and Image Analysis System (Department only)
    The program allows technologists to archive image data from each scanner directly to the Web server and also allows authorized investigators to review animal and patient image/session information and to download image data directly onto the hard disk of their computers. It uses a database and a Web browser as a Graphical User Interface. To access to our system, your machine needs to be registered with our server and also requires an account.

    JANUS: A Java/Internet-Based Nuclear Medicine Computing System (Demonstration only)
    The program allows investigators to display and manipulate images in different formats (PET, PACS, GIF). With this program, images may be displayed, zoomed, reduced, merged and positioned. In addition, it also includes the Region of Interest (ROI) definition, Time Activity Curve (TAC) for dynamic images and as well as other image processing capabilities including color manipulation and image filtering. Through Java, an Internet computer programming language, this program can be run from any computer platform. Janus has been submitted to demonstration in 1998 Society of Nuclear Medicine Annual Meeting (Scientific Exhibit) and received the honor of third place.

    These programs have been used by all investigators in the department for image retrieval and analysis.

    Kinetic Imaging System (KIS)
    Kinetic Imaging Systsem is a fully integrated software system to assist the learning, planning, design, and data analysis of mouse microPET studies. Through computer simulation and animation of tracer kinetics in all tissue organs of a whole animal (based on a realistic 3D mouse atlas), KIS allows users to learn and to evaluate conveniently a multiple of biological, chemical, and experimental factors that could affect the mouse microPET images. Its main module, in fact, allows users to perform "virtual" mouse microPET studies quickly and conveniently without using a real animal. The system serves multiple functions-education, virtual experimentation, experimental design, and image analysis of experimental data. It consists of 4 main modules-"Dictionary", "Simulation", "Image analysis", and "Model Fitting".
    KIS is coded completely in Java to give it the important features of platform-independence, low software maintenance and long product life. It can be run either through the Web from a server or on a stand-alone station.

    Image Quantitation System (JIEIQ)
    Image quantitation is a critical component for molecular imaging and plays an important role in modern drug research. We have developed a Java-based integrated system environment which provides users the capability to quantitate image data. The system is coded completely in Java to achieve platform-independence, low maintenance and long product life. The system is available to users wherever there is an Internet access. It consists of several components: a JANUS image and volume viewer, an image conversion program, a model fitting tool, a plotting package, an image fusion tool (JFuse), a DICOM image sorter and a communication tool.
    JIEIQ is coded completely in Java to give it the important features of platform-independence, low software maintenance and long product life. It can be run either through the Web from a server or on a stand-alone station.

    Molecular Imaging Data Access Portal (MIDAS)
    Molecular Imaging Data Access Portal (MIDAS) is a web-based program that provides a secure access to related microPET data and image. The data includes microPET, CT, Gamma Counter, HPLC, Autoradiography, Optical, Toxicology, Biodistribution, Dosimetry, Kinetic Modeling results, Report, Pathology, RadioChemistry, Animal Information, Cell Culture Assay, System Biology Information and Gene Profiles. Authorized users can upload data and image information to the servers for sharing. Data can be a text file, a document, a spreadsheet, and binary files (JPEG, image data file, etc.). The program search engine will allow users to retrieve valuable information from a complex data pool (i.e. database, computer storage etc.).

    Controlled Access to Radiation Exposure (CARE) System
    Controlled Access to Radiation Exposure (CARE) System is a web-based data communication system that facilitates online submission for Medical Radiation Safety Committee (MRSC) and the Radioactive Drug Research Committee (RDRC). This submission process permits electronic submission, communication and review of protocols that include administration of radiation and/or radioactive materials to human subjects. It is an efficient and secure way to review, track and store submitted protocols. Through this system a labor-intensive paper processing system has been eliminated and protocol review and approval has been drastically shortened.All documents and protocol history is then stored in a secured server that can be easily retrieved through a search field. The system is constructed to adapt easily to any change produced by reviewers or committee members while maintaining the daily operations of any MRSC/RDRC office. Implementation of this system has reduced protocol processing time by nearly 70%.

    Abstracts/Publications

  • Truong DC, Huang SC, Image analysis through the World Wide Web, J. Nucl. Medicine 38:309P, 1997
  • Truong DC, Huang SC, Hoh C, Vu D, Gambhir SS, Phelps ME, A Java/Internet-based platform independent system for nuclear medicine computing, J. Nucl. Medicine 39:278P, 1998
  • Truong DC, Huang SC, Dahlbom M, Ricci A, Sumida R, Phelps ME, Czernin J, An automated image archival system for nuclear medicine, J. Nucl. Med. 41(supp):191P, 2000
  • Truong DC, Huang SC, A Server-based Application Program for Tracer Kinetic Model Fitting in Nuclear Medicine, J. Nuclear Medicine 42:182P, 2001, J. Nucl. Medicine 38:309P, 2001
  • D. Truong, D. Stout, C. Yang, A. Chang, F. Rannou, S. Gambhir, S.C. Huang, M. Phelps, A. Chatziioannou, Multi-system Data Management for Small Animal Imaging, Molecular Imaging and Biology (AMI) Volume 4, Number 4, Supplement 1, July/August 2002, S28
  • Middlekauff H, Yu CL, Sergeeva T, Truong DC, Schelbert HR, Huang SC, Is activation of the rennin-angiotensin system the principle mechanism of exaggerated reflex renal vasoconstriction during exercise in heart failure patients ? A study using O-15 water, J. Nucl. Med. 43:186P, 2002
  • S. C. Huang, D. Truong, H. M. Wu, A. Chatziioannou, A. Wu, M. E. Phelps, Kinetic Imaging System for microPET, Molecular Imaging and Biology (AMI) Volume 6, Number 2, March/April 79:P, 2004
  • S. C. Huang, D. Truong, A. Wu, H. M. Wu, A. Chatziioannou, N. Satyamurthy, J. R. Barrio, M. E. Phelps, Simulation of whole-body kinetics for evaluation of bio-makers, Molecular Imaging and Biology (AMI) Volume 7, Number 2, March/April 135:P, 2005
  • S. C. Huang, H. M. Wu, M. Kreissl, D. Stout, A Chatziioannou, D. Truong, H. R. Schelbert, Evaluation of partial volume effects in mouse cardiac microPET images using a 4D digital mouse phantom (AMI) Volume 7, Number 2, March/April 134:P, 2005
  • Hsiao-Ming Wu, Michael Kreissl, Mayumi Prins, David Truong, Waldemar Ladno, Arion Chatziioannou, Heinrich Shelbert, Sung-Cheng Huang, Derivation of input function from mouse dynamic FDG-PET images: The significance of partial volume correction (PVC), Molecular Imaging and Biology (AMI) Volume 7, Number 2, March/April 162:P, 2005
  • S. C. Huang, A. M. Wu, V. Kenanova, D. Truong, M. E. Phelps, Kinetic Analysis of Bio-Distribution of Labeled SCFV-FC Antibody Fragments in Mouse using Kinetic Imaging System (KIS), J. Nucl. Med. x(supp):xP, 2005
  • C. Wu, W. Ladno, D. Truong, M. Kreissl, M. Prins, H. Schelbert, M. E. Phelps, S. C. Huang, Mouse Plasma and Whole Flood Difference in Fluoro-2-Deoxy-D-Glucose (FDG) Concentration: Implication For Quantitative Mouse FDG-PET Studies, J. Nucl. Med. x(supp):xP, 2005
  • Chin-Lung Yu, Weber Shao, David Truong, Hsiao-Ming WU, Sung-Cheng Huang, An Interactive Whole Body Mouse Anatomy Visualization and Realistic MicroCT/MicroPET Image Simulation Tool - A Kinetic Imaging System (KIS) Extension, Molecular Imaging and Biology (AMI), May/June, 2006
  • S.C. Huang, H.M. Wu, D. Truong, X. Zhang, D.B. Stout, A.F. Chatziioannou, H.R. SchelberT, Domain Dynamic Mouse FDG MicroPET Image Data Set for Evaluation and Validation of Input Function Derivation Methods, 2006 Nuclear Science Symposium, Medical Imaging Conference, Oct/Nov, 2006
  • D. C. Truong, D. Vu, W. Shao, H. Wu, C. Yu, M. Phelps, S. C. Huang, A Java-based Integrated Environment for Image Quantitation (JIEIQ), J. Nucl. Medicine, May 2008, Vol 48, Supplement 2, 203P, SNM 2007 (Washington DC)
  • Wong K-P, Wardak M, Shao W, Zhou Z, Dahlbom M, Smid L, Truong D, Kepe V, Small GW, Barrio JR, and Huang S-C, Movement correction of [18F]FDDNP PET studies for brain amyloid imaging, 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference, pp. 3974-3977, Honolulu, Hawaii, 2007
  • D. C. Truong, D. Stout, A. Chatziioannou, M. Phelps, S. C. Huang, A Data Portal for Molecular Imaging, J. Nucl. Medicine, May 2008, Vol 49, Supplement 1, 157P, SNM 2008 (New Orlean)
  • D. C. Truong, W. Shao, D. Vu, W. Sha, D. Stout, M. Phelps, S. C. Huang, An Automated System for Quantification/Analysis of Mouse PET Images, J. Nucl. Medicine, May 2009, Vol 50, Supplement 2, 174P, SNM 2009 (Toronto)
  • Sung-Cheng Huang, Magnus Dahlbom, Jamshid Maddahi, David Truong, Joel Lazewatsky, Dana Washburn, Heinrich Schelbert, Johannes Czernin, and Michael Phelps, Streamlined quantification of absolute MBF at rest and stress with flurpiridaz F-18 injection PET in normal subjects and patients with coronary artery disease (CAD) J. NUCL. Med. MEETING ABSTRACTS, May 2011; 52: 1114